ASTM-E1163:2016 Edition

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E1163-10(2016) Standard Test Method for Estimating Acute Oral Toxicity in Rats

Published By	Publication Date	Number of Pages
ASTM	2016	3

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Categories: 65.100.99 - Other pesticides and agrochemicals, ASTM

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Description

ASTM E1163-10-Reapproved2016

Historical Standard: Standard Test Method for Estimating Acute Oral Toxicity in Rats

ASTM E1163

Scope

1.1 This test method determines the lethality (LD50 value, slope and 95 % confidence interval (CI)) and signs of acute toxicity from a material using a limited number of rats. The technique used in this test method is referred to as the “Stagewise, Adaptive Dose Method.”2 This test method is an alternative to the classical LD50 test and is applicable to both liquids and solids.

1.2 This test method is not recommended for test materials which typically produce deaths beyond two days postdosing.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

chemicals; LD50; oral toxicity; pesticides; rats;

ICS Code

ICS Number Code 65.100.99 (Other pesticides and agrochemicals)

DOI: 10.1520/E1163-10R16

Additional information

Standard Title	E1163-10(2016) Standard Test Method for Estimating Acute Oral Toxicity in Rats
Published Code	ASTM
Publication Date	2016
Pages Count	3
ICS Codes	65.100.99 - Other pesticides and agrochemicals