ASTM-F750 2002

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F750-87(2002) Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

Published By	Publication Date	Number of Pages
ASTM	2002	3

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Category: ASTM

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Description

ASTM F750-87-Reapproved2002

Historical Standard: Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

ASTM F750

Scope

1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected in the mouse are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

Keywords

acute toxicity tests; biocompatibility; intravenous injection; mouse/mice; test animals

ICS Code

ICS Number Code n/a

DOI: 10.1520/F0750-87R02

Additional information

Standard Title	F750-87(2002) Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse
Published Code	ASTM
Publication Date	2002
Pages Count	3