BSI PD CEN/TR 10345:2013
$189.07
Guideline for statistical data treatment of inter laboratory tests for validation of analytical methods
| Published By | Publication Date | Number of Pages |
| BSI | 2013 | 48 |
This Technical Report is a guideline to carry out the statistical evaluation of data from an inter laboratory test for method validation.
Its purpose is to detail the methodology of ISO 5725-1:1994, ISO 5725-2:1994 and ISO 5725-3:1994 for the treatment of the data collected under the conditions used within the ECISS/TC 102 working groups.
NOTE The present document is not a simplification of the ISO 5725 standard, which is the only reference document.
PDF Catalog
| PDF Pages | PDF Title |
|---|---|
| 4 | Contents Page |
| 5 | Foreword |
| 6 | 1 Scope 2 Normative references 3 Principle 4 Preliminary rules 4.1 First rule (‘to be clear’) |
| 7 | 4.2 Second rule (‘to be modest’) 4.3 Minimal characteristics of data population |
| 8 | 5 Procedure 5.1 Bases 5.2 Raw data examination 5.3 Intra laboratory repeatability variance (Cochran’s test) 5.4 Intra laboratory reproducibility variance (Grubbs’ test) |
| 9 | 5.5 Inter laboratory reproducibility variance (Grubbs’ test) |
| 10 | 5.6 Retained data examination 5.7 Calculation of the variances associated to the tested method 5.8 Treatment for unexpected calculated variances 5.9 Estimation of a function linking variance and level |
| 11 | 6 Report 7 General remarks |
| 12 | Annex A (normative) Steps for the validation of a draft Standard A.1 Decision from a TC to create a working group Figure A.1 — Example of selection of P samples A.2 Laboratories performance on the specified tests |
| 13 | A.3 Statistical work to be done at each level (for each of the P samples) A.3.1 General A.3.2 Intra laboratory repeatability variance (Cochran’s test: ISO 5725-2:1994, 7.3.3) A.3.3 Intra laboratory reproducibility variance (Grubbs’ test: ISO 5725-2:1994, 7.3.4) |
| 14 | A.3.4 Inter laboratories reproducibility variance (Grubbs’ test: ISO 5725-2:1994, 7.3.4) A.3.5 Inter level laboratory performance |
| 15 | Annex B (normative) Synoptic of the operations described in Annex A |
| 20 | Annex C (informative) Examples C.1 Nickel alloys – Determination of tantalum content – Inductively coupled plasma emission spectrometric method – ISO 22725 C.1.1 Original data |
| 21 | C.1.2 Cochran test |
| 22 | C.1.3 New table containing the set of laboratories having the same intra laboratory repeatability variance for further tests |
| 23 | C.1.4 Grubbs test, for intra laboratory reproducibility variance |
| 24 | C.1.5 New table containing the set of laboratories having the same intra laboratory reproducibility variance for further tests C.1.6 Grubbs test, for inter laboratory reproducibility variance |
| 25 | C.1.7 New table containing the set of laboratories having the same inter laboratory reproducibility variance for further evaluations |
| 26 | C.2 Steel and iron – Determination of Nitrogen content –Thermal conductimetric method after fusion in a current of inert gas – ISO 10720 C.2.1 Original data |
| 27 | C.2.2 Cochran test C.2.3 New table containing the set of laboratories having the same intra laboratory repeatability variance for further tests |
| 28 | C.2.4 Grubbs test, for intra laboratory reproducibility variance |
| 30 | C.2.5 New table containing the set of laboratories having the same intra laboratory reproducibility variance for further tests |
| 31 | C.2.6 Grubbs test, for inter laboratory reproducibility variance |
| 32 | C.2.7 New table containing the set of laboratories having the same inter laboratory reproducibility variance for further evaluations |
| 33 | C.3 Steel and iron – Determination of chromium content – Indirect titration method – ISO 15355 C.3.1 Original data C.3.2 Cochran test |
| 34 | C.3.3 New table containing the set of laboratories having the same intra laboratory repeatability variance for further tests C.3.4 Grubbs test, for intra laboratory reproducibility variance |
| 36 | C.3.5 New table containing the set of laboratories having the same intra laboratory reproducibility variance for further tests C.3.6 Grubbs test, for inter laboratory reproducibility variance |
| 37 | C.3.7 New table containing the set of laboratories having the same inter laboratory reproducibility variance for further evaluations |
| 38 | C.4 Steel and iron – Determination of Nitrogen content –Thermal conductimetric method after fusion in a current of inert gas – ISO 10720 C.4.1 Original data |
| 39 | C.4.2 Cochran test C.4.3 New table containing the set of laboratories having the same intra laboratory repeatability variance for further tests |
| 40 | C.4.4 Grubbs test, for intra laboratory reproducibility variance |
| 42 | C.4.5 New table containing the set of laboratories having the same intra laboratory reproducibility variance for further tests C.4.6 Grubbs test, for inter laboratory reproducibility variance |
| 44 | C.4.7 New table containing the set of laboratories having the same inter laboratory reproducibility variance for further evaluations |
| 45 | C.5 General remarks about the examples shown |
| 46 | Bibliography |
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BSI PD CEN/TR 10345:2013
Guideline for statistical data treatment of inter laboratory tests for validation of analytical methods Published…
