BSI PD ISO/TR 22293:2021
$215.11
Evaluation of methods for assessing the release of nanomaterials from commercial, nanomaterial-containing polymer composites
| Published By | Publication Date | Number of Pages |
| BSI | 2021 | 82 |
This document reviews and evaluates the utility of available methods to assess material released from commercial polymer composites in support of product use and safety decisions, and describes what revised or additional methods are needed. The document is not focused on describing methods per se; rather the goal is to describe information that is appropriate for consideration in the selection of methods to support decision-making.
PDF Catalog
| PDF Pages | PDF Title |
|---|---|
| 2 | undefined |
| 7 | Foreword |
| 8 | Introduction |
| 11 | 1 Scope 2 Normative references 3 Terms and definitions |
| 13 | 4 Abbreviations |
| 14 | 5 Understanding the nano-enabled products 5.1 Pathway analysis for the supply chain |
| 18 | 5.2 Matrix and MNM characteristics affecting rate and form of release 5.2.1 General |
| 19 | 5.2.2 Consideration of the polymer used in the composite |
| 20 | 5.2.3 Polymer degradation 5.2.4 Consideration of MNM used in the composite |
| 21 | 5.2.5 Polymer nanocomposites |
| 22 | 5.2.6 Application areas and use phase (or lifecycle) processes |
| 25 | 6 Factors affecting release measurement method selection 6.1 General |
| 26 | 6.2 Forms of release |
| 31 | 6.3 Decision support framework to determine which transformations need consideration with examples |
| 33 | 7 Approaches to detecting and quantifying the released material associated with added manufactured nanomaterials 7.1 General 7.2 Methods for sampling released material 7.2.1 General |
| 34 | 7.2.2 Sampling material released into air |
| 35 | 7.2.3 Sampling material released into water, solids, and biological fluids |
| 36 | 7.3 Methods for preparing samples of released material for subsequent analysis 7.3.1 General 7.3.2 Preparation and analysis of air samples |
| 37 | 7.3.3 Preparation and analysis of waters, solids and biological fluid samples |
| 38 | 7.4 Measurement challenges 7.4.1 General 7.4.2 Surface functionalization and transformations |
| 39 | 7.4.3 Sample collection artefacts 7.4.4 Applicability of a measurement method for a given release media 7.4.5 Sample preparation artefacts 7.4.6 Capability of a measurement method |
| 40 | 7.4.7 Representativeness of measurements 7.4.8 Composition measurements 7.4.9 Polymer stability 7.4.10 Commercial practices |
| 41 | 7.5 Considerations for detection, quantification, and determination of properties of released materials |
| 42 | 7.6 Applicable measurement methods 8 Identification of needs for standards, methods, instrumentation, decision frameworks, and research 8.1 General 8.2 Potential improved/new methods |
| 43 | 8.3 Inter-laboratory studies |
| 44 | 8.4 Protocols and assays 8.5 Opportunities for standardization of methods |
| 45 | 8.6 Decision frameworks |
| 48 | Annex A (informative) Example case studies |
| 67 | Bibliography |
