{"id":402215,"date":"2024-10-20T05:00:07","date_gmt":"2024-10-20T05:00:07","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-iso-44542022\/"},"modified":"2024-10-26T08:52:51","modified_gmt":"2024-10-26T08:52:51","slug":"bs-iso-44542022","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-iso-44542022\/","title":{"rendered":"BS ISO 4454:2022"},"content":{"rendered":"<h4>PDF Catalog<\/h4>\n<table border=\"1px\" class=\"des-table\">\n<tr>\n<th>PDF Pages<\/th>\n<th>PDF Title<\/th>\n<\/tr>\n<tr>\n<td><b>2<b><\/td>\n<td>undefined  <\/td>\n<\/tr>\n<tr>\n<td><b>10<b><\/td>\n<td>Foreword   <\/td>\n<\/tr>\n<tr>\n<td><b>11<b><\/td>\n<td>Introduction   <\/td>\n<\/tr>\n<tr>\n<td><b>13<b><\/td>\n<td>1 Scope  <br \/> 2 Normative references  <br \/> 3 Terms and definitions   <\/td>\n<\/tr>\n<tr>\n<td><b>16<b><\/td>\n<td>4 Abbreviated terms   <\/td>\n<\/tr>\n<tr>\n<td><b>17<b><\/td>\n<td>5 Phenopackets Schema and Requirements  <br \/> 5.1 Phenopacket Schema   <\/td>\n<\/tr>\n<tr>\n<td><b>23<b><\/td>\n<td>5.2 Requirement Levels  <br \/> 5.2.1 General  <br \/> 5.2.2 Multiplicity   <\/td>\n<\/tr>\n<tr>\n<td><b>24<b><\/td>\n<td>5.3 Ontology Use  <br \/> 6 Phenopacket Schema Top-Level Elements  <br \/> 6.1 Phenopacket  <br \/> 6.1.1 General  <br \/> 6.1.2 id  <br \/> 6.1.3 subject   <\/td>\n<\/tr>\n<tr>\n<td><b>25<b><\/td>\n<td>6.1.4 phenotypic_features  <br \/> 6.1.5 measurements  <br \/> 6.1.6 biosamples  <br \/> 6.1.7 interpretation  <br \/> 6.1.8 diseases  <br \/> 6.1.9 medical_actions  <br \/> 6.1.10 files  <br \/> 6.1.11 meta_data  <br \/> 6.2 Family  <br \/> 6.2.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>26<b><\/td>\n<td>6.2.2 id  <br \/> 6.2.3 proband  <br \/> 6.2.4 relatives  <br \/> 6.2.5 pedigree  <br \/> 6.2.6 files  <br \/> 6.2.7 meta_data   <\/td>\n<\/tr>\n<tr>\n<td><b>27<b><\/td>\n<td>6.3 Cohort  <br \/> 6.3.1 General  <br \/> 6.3.2 id  <br \/> 6.3.3 description  <br \/> 6.3.4 members  <br \/> 6.3.5 files  <br \/> 6.3.6 meta_data  <br \/> 7 Phenopackets Building Blocks  <br \/> 7.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>28<b><\/td>\n<td>7.2 Age  <br \/> 7.3 AgeRange  <br \/> 7.4 Biosample  <br \/> 7.4.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>30<b><\/td>\n<td>7.4.2 id  <br \/> 7.4.3 individual_id  <br \/> 7.4.4 derived_from_id  <br \/> 7.4.5 description  <br \/> 7.4.6 sampled_tissue  <br \/> 7.4.7 sample_type  <br \/> 7.4.8 phenotypic_features  <br \/> 7.4.9 measurements   <\/td>\n<\/tr>\n<tr>\n<td><b>31<b><\/td>\n<td>7.4.10 taxonomy  <br \/> 7.4.11 time_at_collection  <br \/> 7.4.12 histological_diagnosis  <br \/> 7.4.13 tumor_progression  <br \/> 7.4.14 tumor_grade  <br \/> 7.4.15 pathological_stage  <br \/> 7.4.16 pathological_tnm_finding  <br \/> 7.4.17 diagnostic_markers  <br \/> 7.4.18 procedure  <br \/> 7.4.19 files   <\/td>\n<\/tr>\n<tr>\n<td><b>32<b><\/td>\n<td>7.4.20 material_sample  <br \/> 7.4.21 sample_processing  <br \/> 7.4.22 sample_storage  <br \/> 7.5 ComplexValue  <br \/> 7.5.1 General  <br \/> 7.5.2 typed_quantities   <\/td>\n<\/tr>\n<tr>\n<td><b>33<b><\/td>\n<td>7.6 Disease  <br \/> 7.6.1 General  <br \/> 7.6.2 term  <br \/> 7.6.3 excluded   <\/td>\n<\/tr>\n<tr>\n<td><b>34<b><\/td>\n<td>7.6.4 onset  <br \/> 7.6.5 resolution  <br \/> 7.6.6 disease_stage  <br \/> 7.6.7 clinical_tnm_finding  <br \/> 7.6.8 primary_site  <br \/> 7.6.9 laterality  <br \/> 7.7 DoseInterval  <br \/> 7.7.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>35<b><\/td>\n<td>7.7.2 quantity  <br \/> 7.7.3 schedule_frequency  <br \/> 7.7.4 interval  <br \/> 7.8 DrugType  <br \/> 7.8.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>36<b><\/td>\n<td>7.9 Evidence  <br \/> 7.9.1 General  <br \/> 7.9.2 evidence_code  <br \/> 7.9.3 Reference  <br \/> 7.10 ExternalReference  <br \/> 7.10.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>37<b><\/td>\n<td>7.10.2 id  <br \/> 7.10.3 reference  <br \/> 7.10.4 description  <br \/> 7.11 File  <br \/> 7.11.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>38<b><\/td>\n<td>7.11.2 uri  <br \/> 7.11.3 individual_to_file_identifiers  <br \/> 7.11.4 file_attributes  <br \/> 7.12 GeneDescriptor  <br \/> 7.12.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>39<b><\/td>\n<td>7.12.2 value_id   <\/td>\n<\/tr>\n<tr>\n<td><b>40<b><\/td>\n<td>7.12.3 symbol  <br \/> 7.12.4 description  <br \/> 7.12.5 alternate_ids  <br \/> 7.12.6 alternate_symbols  <br \/> 7.12.7 xrefs  <br \/> 7.13 GenomicInterpretation  <br \/> 7.13.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>41<b><\/td>\n<td>7.13.2 subject_or_biosample_id  <br \/> 7.13.3 interpretation_status  <br \/> 7.13.4 call  <br \/> 7.14 GestationalAge  <br \/> 7.14.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>42<b><\/td>\n<td>7.15 Individual  <br \/> 7.15.1 General  <br \/> 7.15.2 id   <\/td>\n<\/tr>\n<tr>\n<td><b>43<b><\/td>\n<td>7.15.3 alternate_ids  <br \/> 7.15.4 date_of_birth  <br \/> 7.15.5 time_at_last_encounter   <\/td>\n<\/tr>\n<tr>\n<td><b>44<b><\/td>\n<td>7.15.6 vital_status  <br \/> 7.15.7 sex  <br \/> 7.15.8 karyotypic_sex  <br \/> 7.15.9 gender  <br \/> 7.15.10 taxonomy  <br \/> 7.16 Interpretation  <br \/> 7.16.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>45<b><\/td>\n<td>7.16.2 id  <br \/> 7.16.3 progress_status   <\/td>\n<\/tr>\n<tr>\n<td><b>46<b><\/td>\n<td>7.16.4 diagnosis  <br \/> 7.16.5 summary  <br \/> 7.17 KaryotypicSex   <\/td>\n<\/tr>\n<tr>\n<td><b>47<b><\/td>\n<td>7.18 Measurement  <br \/> 7.18.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>48<b><\/td>\n<td>7.18.2 description  <br \/> 7.18.3 assay  <br \/> 7.18.4 value  <br \/> 7.18.5 time_observed  <br \/> 7.18.6 procedure  <br \/> 7.19 MedicalAction  <br \/> 7.19.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>49<b><\/td>\n<td>7.19.2 action  <br \/> 7.19.3 treatment_target  <br \/> 7.19.4 treatment_intent  <br \/> 7.19.5 response_to_treatment  <br \/> 7.19.6 adverse_events  <br \/> 7.19.7 treatment_termination_reason  <br \/> 7.20 MetaData  <br \/> 7.20.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>50<b><\/td>\n<td>7.20.2 created  <br \/> 7.20.3 created_by  <br \/> 7.20.4 submitted_by  <br \/> 7.20.5 resources   <\/td>\n<\/tr>\n<tr>\n<td><b>51<b><\/td>\n<td>7.20.6 updates  <br \/> 7.20.7 phenopacket_schema_version  <br \/> 7.20.8 external_references  <br \/> 7.21 OntologyClass  <br \/> 7.21.1 General  <br \/> 7.21.2 id  <br \/> 7.21.3 label   <\/td>\n<\/tr>\n<tr>\n<td><b>52<b><\/td>\n<td>7.22 Pedigree  <br \/> 7.22.1 General  <br \/> 7.22.2 persons   <\/td>\n<\/tr>\n<tr>\n<td><b>54<b><\/td>\n<td>7.23 PhenotypicFeature  <br \/> 7.23.1 General  <br \/> 7.23.2 description  <br \/> 7.23.3 type   <\/td>\n<\/tr>\n<tr>\n<td><b>55<b><\/td>\n<td>7.23.4 excluded  <br \/> 7.23.5 severity  <br \/> 7.23.6 modifiers  <br \/> 7.23.7 onset  <br \/> 7.23.8 resolution  <br \/> 7.23.9 evidence  <br \/> 7.24 Procedure  <br \/> 7.24.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>56<b><\/td>\n<td>7.24.2 code  <br \/> 7.24.3 body site  <br \/> 7.24.4 performed  <br \/> 7.25 Quantity  <br \/> 7.25.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>57<b><\/td>\n<td>7.25.2 unit  <br \/> 7.25.3 value  <br \/> 7.25.4 reference_range  <br \/> 7.26 RadiationTherapy  <br \/> 7.26.1 General  <br \/> 7.26.2 modality  <br \/> 7.26.3 body_site   <\/td>\n<\/tr>\n<tr>\n<td><b>58<b><\/td>\n<td>7.26.4 dosage  <br \/> 7.26.5 fractions  <br \/> 7.27 ReferenceRange  <br \/> 7.27.1 General  <br \/> 7.27.2 unit  <br \/> 7.27.3 low  <br \/> 7.27.4 high  <br \/> 7.28 Resource  <br \/> 7.28.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>59<b><\/td>\n<td>7.28.2 id   <\/td>\n<\/tr>\n<tr>\n<td><b>60<b><\/td>\n<td>7.28.3 name  <br \/> 7.28.4 url  <br \/> 7.28.5 version  <br \/> 7.28.6 namespace_prefix  <br \/> 7.28.7 iriPrefix  <br \/> 7.28.8 CURIE   <\/td>\n<\/tr>\n<tr>\n<td><b>61<b><\/td>\n<td>7.28.9 Identifier resolution  <br \/> 7.29 Sex  <br \/> 7.30 TherapeuticRegimen  <br \/> 7.30.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>62<b><\/td>\n<td>7.30.2 identifier  <br \/> 7.30.3 start_time  <br \/> 7.30.4 end_time  <br \/> 7.30.5 regimen_status  <br \/> 7.31 TimeElement  <br \/> 7.31.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>63<b><\/td>\n<td>7.31.2 gestational_age  <br \/> 7.31.3 age  <br \/> 7.31.4 age_range  <br \/> 7.31.5 ontology_class  <br \/> 7.31.6 timestamp  <br \/> 7.31.7 interval  <br \/> 7.32 TimeInterval  <br \/> 7.32.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>64<b><\/td>\n<td>7.32.2 start  <br \/> 7.32.3 end  <br \/> 7.33 Timestamp  <br \/> 7.34 Treatment  <br \/> 7.34.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>66<b><\/td>\n<td>7.34.2 agent  <br \/> 7.34.3 route_of_administration  <br \/> 7.34.4 dose_intervals  <br \/> 7.34.5 drug_type  <br \/> 7.34.6 cumulative_dose  <br \/> 7.35 Update  <br \/> 7.35.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>67<b><\/td>\n<td>7.35.2 timestamp  <br \/> 7.35.3 updated_by  <br \/> 7.35.4 comment  <br \/> 7.36 Value  <br \/> 7.36.1 General  <br \/> 7.36.2 value  <br \/> 7.37 VariationDescriptor  <br \/> 7.37.1 General   <\/td>\n<\/tr>\n<tr>\n<td><b>70<b><\/td>\n<td>7.37.2 id  <br \/> 7.37.3 variation  <br \/> 7.37.4 label  <br \/> 7.37.5 description  <br \/> 7.37.6 gene_context  <br \/> 7.37.7 expression  <br \/> 7.37.8 vcf_record   <\/td>\n<\/tr>\n<tr>\n<td><b>71<b><\/td>\n<td>7.37.9 xrefs  <br \/> 7.37.10 alternate_labels  <br \/> 7.37.11 extensions  <br \/> 7.37.12 molecule_context  <br \/> 7.37.13 structural_type   <\/td>\n<\/tr>\n<tr>\n<td><b>72<b><\/td>\n<td>7.37.14 vrs_ref_allele_seq  <br \/> 7.37.15 allelic_state  <br \/> 7.38 VariantInterpretation  <br \/> 7.38.1 General  <br \/> 7.38.2 acmg_pathogenicity_classification   <\/td>\n<\/tr>\n<tr>\n<td><b>73<b><\/td>\n<td>7.38.3 therapeutic_actionability  <br \/> 7.38.4 variant  <br \/> 7.39 VitalStatus  <br \/> 7.39.1 General  <br \/> 7.39.2 status   <\/td>\n<\/tr>\n<tr>\n<td><b>74<b><\/td>\n<td>7.39.3 time_of_death  <br \/> 7.39.4 cause_of_death  <br \/> 7.39.5 survival_time_in_days   <\/td>\n<\/tr>\n<tr>\n<td><b>75<b><\/td>\n<td>Annex A (informative) Working with Phenopackets   <\/td>\n<\/tr>\n<tr>\n<td><b>83<b><\/td>\n<td>Annex B (informative) Ontologies   <\/td>\n<\/tr>\n<tr>\n<td><b>86<b><\/td>\n<td>Annex C (informative) Rare Disease Example   <\/td>\n<\/tr>\n<tr>\n<td><b>89<b><\/td>\n<td>Annex D (informative) Cancer Example   <\/td>\n<\/tr>\n<tr>\n<td><b>93<b><\/td>\n<td>Annex E (informative) COVID-19 Example   <\/td>\n<\/tr>\n<tr>\n<td><b>98<b><\/td>\n<td>Bibliography   <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p><b>Genomics informatics. Phenopackets: A format for phenotypic data exchange<\/b><\/p>\n<table class=\"shortdes-table\" style=\"width: 100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td>Published By<\/td>\n<td>Publication Date<\/td>\n<td>Number of Pages<\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/pdfstandards.shop\/product-category\/publishers\/bsi\/\"><b>BSI<\/b><\/a><\/td>\n<td>2022<\/td>\n<td>102<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":402222,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[704,2641],"product_tag":[],"class_list":{"0":"post-402215","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-35-240-80","7":"product_cat-bsi","9":"first","10":"instock","11":"sold-individually","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/402215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/402222"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=402215"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=402215"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=402215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}