{"id":425450,"date":"2024-10-20T06:56:55","date_gmt":"2024-10-20T06:56:55","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bsi-23-30427228-dc-2023\/"},"modified":"2024-10-26T13:06:02","modified_gmt":"2024-10-26T13:06:02","slug":"bsi-23-30427228-dc-2023","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bsi-23-30427228-dc-2023\/","title":{"rendered":"BSI 23\/30427228 DC 2023"},"content":{"rendered":"

PDF Catalog<\/h4>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
PDF Pages<\/th>\nPDF Title<\/th>\n<\/tr>\n
1<\/td>\n30427228-NC.pdf <\/td>\n<\/tr>\n
3<\/td>\nISO_DIS 20688-2 ed.1 – id.75852 Enquiry PDF (en).pdf <\/td>\n<\/tr>\n
7<\/td>\nForeword <\/td>\n<\/tr>\n
8<\/td>\nIntroduction <\/td>\n<\/tr>\n
9<\/td>\n1 Scope
2 Normative references
3 Terms and definitions <\/td>\n<\/tr>\n
12<\/td>\n4 General requirements for quality management
4.1 General requirements
4.2 Control of documents <\/td>\n<\/tr>\n
13<\/td>\n4.3 Quality management system
4.4 Biorisk management and safety control <\/td>\n<\/tr>\n
14<\/td>\n5 Requirements for resource management
5.1 Facilities and environmental condition
5.2 Equipment and instruments
5.3 Raw materials <\/td>\n<\/tr>\n
15<\/td>\n5.4 Personnel
6 Biosafety and biosecurity requirements
6.1 General
6.2 DNA sequence screening mechanism
7 Requirements for quality control in production
7.1 General <\/td>\n<\/tr>\n
16<\/td>\n7.2 Quality control in synthetic gene fragments production
7.2.1 General
7.2.2 Sequence design
7.2.3 Assembly
7.2.4 Purification
7.2.5 Product preservation
7.3 Quality control in synthetic gene production
7.3.1 General <\/td>\n<\/tr>\n
17<\/td>\n7.3.2 Colony Screening
7.3.3 DNA preparation from the host cell
7.3.4 Sequence Verification
7.3.5 Product preservation
7.4 Quality control in synthetic genome production
7.4.1 General <\/td>\n<\/tr>\n
18<\/td>\n7.4.2 Assembly
7.4.3 Sequence verification
8 Requirements for product quality
8.1 Synthetic gene fragments
8.1.1 General
8.1.2 Yield
8.1.3 Purity
8.1.4 Size <\/td>\n<\/tr>\n
19<\/td>\n8.1.5 Gene cloning accuracy
8.2 Synthetic genes
8.2.1 General
8.2.2 Yield
8.2.3 Purity
8.2.4 Sequence
8.2.5 Integrity <\/td>\n<\/tr>\n
20<\/td>\n8.2.6 Residual impurities analysis
8.2.7 Supercoiled plasmid
8.2.8 Bioburden
8.2.9 Specific quality indicators for synthetic DNA libraries <\/td>\n<\/tr>\n
21<\/td>\n8.3 Synthetic genome
8.3.1 General
8.3.2 sequence
9 Delivered\/Synthesized Material Specifications <\/td>\n<\/tr>\n
22<\/td>\nAnnex\u20acA (informative) Equipment and device list and control requirements <\/td>\n<\/tr>\n
24<\/td>\nAnnex\u20acB (informative) Exemplary quality measurement methods <\/td>\n<\/tr>\n
26<\/td>\nAnnex\u20acC (informative) Electrophoretogram <\/td>\n<\/tr>\n
29<\/td>\nAnnex\u20acD (informative) Sanger sequencing <\/td>\n<\/tr>\n
30<\/td>\nAnnex\u20acE (informative) Massively Parallel Sequencing (MPS) <\/td>\n<\/tr>\n
33<\/td>\nAnnex\u20acF (informative) Additional quality control options for synthetic gene fragments <\/td>\n<\/tr>\n
34<\/td>\nAnnex\u20acG (informative) The ranks of the risk posed by DNA products <\/td>\n<\/tr>\n
35<\/td>\nBibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

BS ISO 20688-2. Biotechnology. Nucleic acid synthesis – Part 2. General definitions and requirements for the production and quality control of synthesized gene fragments, genes, and genomes<\/b><\/p>\n\n\n\n\n
Published By<\/td>\nPublication Date<\/td>\nNumber of Pages<\/td>\n<\/tr>\n
BSI<\/b><\/a><\/td>\n2023<\/td>\n36<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":425460,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[2641],"product_tag":[],"class_list":{"0":"post-425450","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bsi","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/425450","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/425460"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=425450"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=425450"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=425450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}