{"id":279707,"date":"2024-10-19T18:53:04","date_gmt":"2024-10-19T18:53:04","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-en-iso-10993-162017\/"},"modified":"2024-10-25T15:27:21","modified_gmt":"2024-10-25T15:27:21","slug":"bs-en-iso-10993-162017","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-en-iso-10993-162017\/","title":{"rendered":"BS EN ISO 10993-16:2017"},"content":{"rendered":"
This document provides principles on designing and performing toxicokinetic studies relevant to medical devices. Annex A describes the considerations for inclusion of toxicokinetic studies in the biological evaluation of medical devices.<\/p>\n
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
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2<\/td>\n | National foreword <\/td>\n<\/tr>\n | ||||||
4<\/td>\n | European foreword <\/td>\n<\/tr>\n | ||||||
6<\/td>\n | Foreword <\/td>\n<\/tr>\n | ||||||
7<\/td>\n | Introduction <\/td>\n<\/tr>\n | ||||||
9<\/td>\n | 1 Scope 2 Normative references 3 Terms and definitions <\/td>\n<\/tr>\n | ||||||
11<\/td>\n | 4 Principles for design of toxicokinetic studies 5 Guidance on test methods 5.1 General considerations <\/td>\n<\/tr>\n | ||||||
13<\/td>\n | 5.2 Guidance on specific types of test 5.2.1 General 5.2.2 Absorption 5.2.3 Distribution <\/td>\n<\/tr>\n | ||||||
14<\/td>\n | 5.2.4 Metabolism and excretion <\/td>\n<\/tr>\n | ||||||
15<\/td>\n | Annex A (normative) Circumstances in which toxicokinetic studies shall be considered <\/td>\n<\/tr>\n | ||||||
17<\/td>\n | Bibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" Biological evaluation of medical devices – Toxicokinetic study design for degradation products and leachables<\/b><\/p>\n |